- A noted Manhattan nightclub denizen as a college student, she was the subject of a 1986 New York Times Magazine profile written by Maureen Dowd.
- Wrote, composed and performed in Positive Me, a 1989 musical piece about AIDS produced by off-Broadway's LaMama theater company; Thomas Gibson was in the cast.
- Made her film debut as a makeup artist in Oliver Stone's The Doors (1991).
- Voiced the role of Lex Luthor's aide Mercy Graves in Superman: The Animated Series, as well as in the Justice League Unlimited cartoon series; also voiced Crystal Steele in the Blade Runner CD-ROM game.
- Is a longtime vegetarian.
- Does volunteer work for the Best Friends Animal Sanctuary, Save the Children, Planned Parenthood and AmFAR.
- 2011, People's Choice Awards — Favorite TV Drama Actress: Winner
- 2008, Screen Actors Guild Awards — Outstanding Performance by an Ensemble in a Drama Series: Nominee
- Alvin Edelstein — Father
- Robert Russell — Husband
- Bonnie Edelstein — Mother
- Attended New York University, Tisch School of the Arts, New York, New York, United States