- Began acting at age 12, appearing in programs such as Popular Mechanics for Kids and Are You Afraid of the Dark?
- Has a maple-leaf tattoo on his chest in honor of his Canadian heritage.
- Was cast in Knocked Up in the role of Jay, a character that writer-director Judd Apatow created with Baruchel in mind.
- Was thanked by Clint Eastwood in his Best Picture Oscar acceptance speech for Million Dollar Baby after playing the role of Danger Barch in the film.
- 2010, Genie Awards — Best Performance by an Actor in a Leading Role: Nominee
- 2014, Canadian Screen Awards — Performance by an Actor in a Supporting Role: Nominee
- 2013, Canadian Screen Awards — Performance by an Actor in a Supporting Role: Nominee
- 2013, Canadian Screen Awards — Adapted Screenplay: Nominee
- Serge Baruchel — Father
- Taylor Baruchel — Sister
- Alison Pill — Ex-fiancée
- Robyne Ropell — Mother
- Robyne Baruchel — Mother
- Sarah Lind — Ex-significant Other
- Taylor — Sister
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