Abigail holds Jackson prisoner in order to extract information from him that is critical to her secret master plan. Meanwhile, the team faces a mid-air crisis when their plane experiences an electrical malfunction.
Jackson and Logan discover a link between the hybrid attacks that occur in Portland and New York. Meanwhile, Mitch is interrogated by a woman claiming to be his daughter; and a new development in Abraham's research into the sterility crisis endangers his family.
Ten years after the animals were cured but at the cost of sterilizing the human population, a new threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures focused on destroying mankind, on the third-season premiere.