In the series finale, Quinlan devises a desperate plan, but the costs are enormous. Eph wrestles with his conscience; Fet undertakes a suicide mission; and Dutch and Gus dig in for battle as humankind makes its final stand against the Master and his Strain.
An unexpected guest brings old conflicts to the surface, dividing our heroes, threatening the group's trust. With questionable new intel in hand, they launch a make-or-break final assault on the Master.
His health failing, Setrakian ignores Eph's warnings, pushing himself to the limit in his quest for victory and revenge. Also: Fet and Quinlan race back to Manhattan, while the Master seals off the city and prepares to eliminate them all.
Fet and Quinlan have to figure out how to get the nuclear bomb back to New York, while a desperate Eichhorst draws near. Also: love-struck Zack tries to learn more about his new crush, but makes a devastating discovery.
Fet and Quinlan are hot on the trail of a convoy carrying their prized nuclear weapon. Also: Eph and Alex search for clues to uncover the Master's plan for the fate of the human race and Dutch is trapped by a familiar enemy and encounters an old friend.
Dutch is forced to make a deal with Desai while she plots to escape a strigoi breeding facility. Also: Eph and Alex try to unearth secrets of the Partnership's new plan but face consequences of their last attack and Gus and Creem face off against a gang encroaching on their turf.
Quinlan and Fet discover that stealing a nuclear warhead isn't easy when they encounter an unexpected enemy. Also: Eph and Alex concoct a new weapon to use against the strigoi and Zack discovers a love interest.
Imprisoned as a subject in a strigoi breeding program, Dutch is desperate to escape and find Setrakian. Also: Gus recruits his cousin for the inside job that will put his gang at the top of the new world's underground economy, but Creem is suspicious of his business partner's ambitions.
In the Season 4 premiere, Night Eternal has set in following the nuclear war and Eph abandons New York for Philadelpha, where he encounters new fighters who rekindle his drive to fight back. Elsewhere: Setrakian tasks Fet and Quinlan to find a new means of stopping the Master.