Episode Detail: Win, Lose and Kaboom! - The Adventures of Jimmy Neutron, Boy Genius
Jimmy and his pals are hurled into space where they meet up with a bizarre TV host (Tim Allen), who pits them against aliens on an otherworldly reality show. They're playing for a big prize: the safety of their home planets. The losers' planets will be destroyed, and one of the aliens (Alyssa Milano) wants Jimmy to help her thwart that evil plan.