Supernatural: Route 666 Trailer
Dean (Jensen Ackles) is contacted by his first love Cassie (Megalyn Echikunwoke), an African-America girl, who asks him to come to Mississippi to investigate a string of racially motivated murders. Each murder is linked to a mysterious truck that seems to have no driver and leave no tracks. Sam (Jared Padalecki) is stunned to see this new side of his brother as Dean struggles to come to grips with the residual feelings he has for Cassie.
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- Premiered: September 21, 2006
- Rating: TV-14
- Premise: Two brothers hunt demons, ghosts and other supernatural entities as they investigate crimes caused by paranormal forces. (more)