Season 4, Episode 6 Yellow Fever
First Aired: October 23, 2008
Several men die from fright after being infected with a mysterious illness that causes acute anxiety, which leads to total terror. Sam and Dean investigate, and Dean becomes infected. Sam desperately searches for a cure before Dean dies and is sent back to hell.
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- Premiered: September 21, 2006
- Rating: TV-14
- Premise: Two brothers hunt demons, ghosts and other supernatural entities as they investigate crimes caused by paranormal forces. (more)
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The show gave the perfect shoutout to Papa Winchester (Jeffrey Dean Morgan).