Motoko's concerns for her father-in-law's health are brushed off as exaggerated worry, but soon her husband and children fall victim to the Shiki's curse. She calculates her revenge while wandering the bloodied streets alone amidst the panic.
The struggle between the survivors of Sotoba and their neighbors-turned-demons continues. The hunt goes underground as Nao and a group of Shiki take refuge in the farmers' irrigation tunnel in hopes of escaping the slaughter above.
Toshio leads those who haven't joined the Shiki—or fled the village—on a raging, blood-soaked hunt, but there's still one place they haven't looked. As the vampires strike back, Seishin continues his watch over Sunako.
Toshio realizes that the source of the deadly illness won't be found using conventional methods. He and Seishin observe a patient overnight to catch any changes in her condition—or possible moonlight visitors.
After visiting the surviving families of the deceased, Seishin discovers a peculiar similarity amongst every victim. Natsuno is tortured by helplessness as his visions of Megumi become terrifyingly close to reality.
Another villager displays the symptoms of the epidemic, but Toshio notices a new clue during a closer inspection. The family that moved into the mansion on the hill visit town, while their little girl shows a disturbing interest in Seishin.