Samantha Who?

An accident victim awakens from an eight-day coma with amnesia and must start over. As she does, she learns she wasn't a nice person.

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Season 2, Episode 3 The Pill

First Aired: October 27, 2008

Sam enters a clinical trial for people with memory loss, and the pills help her regain memory fragments. Meanwhile, Andrea and Dena are mistaken for a gay couple, and Andrea insists that, if she were gay, she could hook up with a much hotter woman than Dena.

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Guest Cast

Older Woman
Tony Hale Dr. Andy Adams
Carol
Cute Guy
Crying Kid

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  • Premiered: October 15, 2007
  • Rating: TV-14
  • Premise: An accident victim awakens from an eight-day coma with amnesia and must start over. As she does, she learns she wasn't a nice person. (more)
Cast
Christina Applegate Christina Applegate Samantha `Sam' Newly
Jennifer Esposito Jennifer Esposito Andrea
Kevin Dunn Kevin Dunn Howard
Melissa McCarthy Melissa McCarthy Dena
Tim Russ Tim Russ Frank
Jean Smart Jean Smart Regina

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