In the series finale, Miles' crew plan an attack on the Patriots, but then they're forced to improvise because of a war between other parties. Meanwhile, Neville goes after President Davis; and Aaron and Rachel try to save Priscilla.
Neville and Monroe team up to defeat the Patriots. Meanwhile, Rachel encounters the nanotech as she looks for Aaron; and Miles, Charlie and Gene attempt to swipe the Patriots' stockpile of mustard gas.
Miles and Monroe face mustard gas from Truman, so they prepare to fight at the same brutal level, much to Rachel's chagrin. Meanwhile, Aaron fears the strength of the nanotech; and Neville deals with his own challenge from the Patriots.
Miles finds himself alone and injured after an encounter with the Texas Rangers. Meanwhile, Neville seeks answers from Charlie regarding Jason's whereabouts; and Aaron discovers how hardworking the nanotech is.
Miles and Gene look for allies in Willoughby. Meanwhile, Monroe launches a surprise attack on the Patriots; Neville's actions jeopardize him and Jason; and Aaron and Priscilla remain steadfast in their journey.
Monroe, Charlie and Connor return to Willoughby and discover the town now has a reeducation center. Meanwhile, Rachel and Miles clash over the extremes they'll go to when fighting the Patriots; and Neville and Jason gain an ally and learn about the Patriots' history.
Survival in New Vegas may come at a high cost for Monroe and Connor. Elsewhere, Aaron clashes with Priscilla regarding the nano code; and Miles is unsure about how honest Neville and Jason are being about their desire to defeat the Patriots.
Aaron and Rachel speculate about the extreme effects of nano technology; Miles tries to convince an old comrade to help bring down the Patriots; Charlie has a surprise for Miles and her mother; and Secretary Allenford has information that Neville needs.
The Charlie-Monroe dynamic evolves; as their wounds heal, Miles and Rachel plot resistance to what they fear may be a Patriot occupation; Neville manipulates Patriot power brokers; and Aaron's mind works overtime.
Rachel attempts to rescue Miles; Neville and Jason are surprised by refugees; Charlie and Adam disagree over what to do with Monroe; Willoughby is threatened by legions of Tribesmen; and Aaron faces death.
Miles' life is in danger after he's captured. Meanwhile, Charlie is adamant about finding Monroe; Rachel and her father, Dr. Porter, attempt to revive Aaron; and Neville works up a plan to infiltrate the Patriots.
In the Season 2 premiere, Miles, Aaron and Rachel find themselves in a small town in Texas where Rachel comes across a figure from her past; Charlie is on a mission in the Plains Nation; and Neville and Jason search a refugee camp for a loved one.