The interaction of four adult sisters---the Sorelli siblings---an intelligent and quirky group living in Manhattan, who, despite their differences, are best friends. They all have a say in other's lives, which sometimes is great and sometimes not so good. Which means the show is seriocomic in the tradition of `Friends,' whose co-creator, Marta Kauffman, developed the series.


Jennifer Esposito Ginnie Sorelli
Kiele Sanchez Anne Sorelli
Lizzy Caplan Marjee Sorelli
Laura Breckenridge Rose Sorelli