The interaction of four adult sisters---the Sorelli siblings---an intelligent and quirky group living in Manhattan, who, despite their differences, are best friends. They all have a say in other's lives, which sometimes is great and sometimes not so good. Which means the show is seriocomic in the tradition of `Friends,' whose co-creator, Marta Kauffman, developed the series.


Guest Stars

Kyle Howard
Joel, Joel Corcoran
13 Episodes (2005-2006)
Tom Irwin
Joe, Joe Sorelli
12 Episodes (2005-2006)
Christine Ebersole
9 Episodes (2005-2006)
Chris Carmack
Alex, Alex Brody
9 Episodes (2005-2006)
Dan Futterman
8 Episodes (2005-2006)
Dennis Boutsikaris
Kasnov, Professor Kasnov
4 Episodes (2005-2006)
John Prosky
Dr. Gorenberg
3 Episodes (2005-2006)
Dana Delany
2 Episodes (2005-2006)
Roger Rees
Robert George Spencer III
2 Episodes (2005-2006)
Jaime Ray Newman
2 Episodes (2006-2006)
Amy Hill
2 Episodes (2006-2006)
Sarah K. Peterson
Marjee (age 8), Young Marjee
2 Episodes (2005-2006)
Al White
Elevator Operator
1 Episode (2005)
Judith Ivey
Millicent Spencer
1 Episode (2005)
Adriana DeMeo
Tanya Torcoletti
1 Episode (2005)
James Snyder
Cute Young Man (Collin)
1 Episode (2005)
Ping Wu
Mr. Takashi
1 Episode (2005)