A 23-year-old woman who weighs more than 600 pounds is dependent on her family and her boyfriend for the simplest tasks, so she decides to have weight-loss surgery that will force her to move 2000 miles away from her loved ones.
A 26-year-old man who weighs more than 700 pounds has a large growth on one side and skin that is practically splitting apart, but his mother must alter both of their eating habits before he can be recommended for gastric bypass surgery.
The Season 5 premiere features twins who weigh more than 1100 pounds combined and are worried about losing each other to obesity, but an emergency during weight-loss surgery could make that happen sooner than later.
A 670-lb. woman is forced to live in her parents' house with her husband, but hopes weight-loss surgery will save her life and marriage as well as give her a chance to become more independent and start a family.