Premise

A daily talk show featuring celebrity interviews, human-interest stories and segments on health, beauty and fashion.

Cast

Former Cast

Guest Stars

Jude Law
18 Episodes (2001-2015)
Pat Sajak
17 Episodes (2002-2009)
Zac Efron
16 Episodes (2007-2016)
Paul Rudd
14 Episodes (2002-2015)
Tom Hanks
14 Episodes (2002-2015)
Lucy Liu
13 Episodes (2003-2016)
Tina Fey
11 Episodes (2006-2016)
Diddy
10 Episodes (2001-2008)
Eric Dane
10 Episodes (2007-2016)
Jewel
10 Episodes (2003-2011)
Amy Adams
9 Episodes (2008-2016)
Jack Black
9 Episodes (2003-2015)
Lisa Rinna
9 Episodes (2001-2015)
Matt Damon
9 Episodes (2003-2016)
Mike Myers
9 Episodes (2002-2010)
Tony Danza
9 Episodes (2001-2007)
Vin Diesel
9 Episodes (2002-2015)
Jon Hamm
9 Episodes (2008-2015)
Téa Leoni
8 Episodes (2001-2014)
Will Smith
8 Episodes (2001-2007)
Drew Carey
8 Episodes (2001-2014)
Ashanti
8 Episodes (2002-2012)
John Cena
8 Episodes (2006-2015)
Raven
8 Episodes (2005-2012)
Tea Leoni
8 Episodes (2001-2014)
Andy Cohen
8 Episodes (2011-2016)
Clive Owen
7 Episodes (2006-2015)
Ice Cube
7 Episodes (2002-2016)
Liv Tyler
7 Episodes (2001-2014)
Mel B.
7 Episodes (2008-2016)
Tim Allen
7 Episodes (2001-2010)
Molly Sims
7 Episodes (2002-2011)
Seth Rogen
7 Episodes (2007-2015)
Ashanti
7 Episodes (2002-2012)
Common
7 Episodes (2005-2016)
Ludacris
7 Episodes (2003-2010)
Tim Gunn
7 Episodes (2006-2012)
Ne-Yo
7 Episodes (2006-2015)
Guy Fieri
7 Episodes (2008-2014)
Beth Behrs
7 Episodes (2012-2016)
Alan Alda
6 Episodes (2005-2009)
Eva Mendes
6 Episodes (2007-2011)
Jon Cryer
6 Episodes (2004-2015)
Rob Lowe
6 Episodes (2003-2015)
Rose Byrne
6 Episodes (2011-2016)
Tyra Banks
6 Episodes (2004-2015)
50 Cent
6 Episodes (2005-2016)
Jo Frost
6 Episodes (2005-2010)
Joss Stone
6 Episodes (2005-2015)
Usher
6 Episodes (2001-2014)
Cat Deeley
6 Episodes (2008-2012)
Emma Stone
6 Episodes (2011-2014)
Andy Dick
5 Episodes (2001-2005)
Chris Noth
5 Episodes (2003-2016)
Diane Lane
5 Episodes (2003-2010)
Jason Lee
5 Episodes (2006-2011)
Jim Carrey
5 Episodes (2003-2011)
Lisa Rinna
5 Episodes (2001-2015)
LL Cool J
5 Episodes (2009-2015)
Sara Rue
5 Episodes (2003-2010)
Tom Cruise
5 Episodes (2004-2010)
Val Kilmer
5 Episodes (2002-2006)
Ciara
5 Episodes (2004-2015)
Paula Deen
5 Episodes (2006-2011)
Tom Brokaw
5 Episodes (2001-2015)
Chris Pine
5 Episodes (2012-2016)
David Cook
5 Episodes (2008-2011)
Ken Jeong
5 Episodes (2011-2016)
Seal
5 Episodes (2003-2016)
Anne Heche
4 Episodes (2002-2010)
Bill Cosby
4 Episodes (2001-2003)
Dean Cain
4 Episodes (2001-2006)
Elton John
4 Episodes (2001-2014)
Ice-T
4 Episodes (2006-2012)
Jane Fonda
4 Episodes (2007-2015)
John Walsh
4 Episodes (2007-2010)
Jon Voight
4 Episodes (2002-2007)
Kate Walsh
4 Episodes (2007-2012)
Kevin Hart
4 Episodes (2012-2016)
Lucy Liu
4 Episodes (2003-2016)
Madonna
4 Episodes (2003-2007)
Meg Ryan
4 Episodes (2004-2016)
Mila Kunis
4 Episodes (2002-2016)
Noah Wyle
4 Episodes (2004-2012)
Ray Liotta
4 Episodes (2001-2016)
Taye Diggs
4 Episodes (2001-2016)
Idris Elba
4 Episodes (2012-2016)
Ty Burrell
4 Episodes (2010-2014)
Clay Aiken
4 Episodes (2004-2006)
Shakira
4 Episodes (2001-2006)
Eva La Rue
4 Episodes (2002-2012)
Mehmet Oz
4 Episodes (2007-2008)
Babyface
4 Episodes (2001-2014)
Cat Cora
4 Episodes (2005-2012)
Dido
4 Episodes (2001-2013)
Jayma Mays
4 Episodes (2011-2013)
Jill Scott
4 Episodes (2001-2015)
Jill Scott
4 Episodes (2001-2015)
Masi Oka
4 Episodes (2007-2010)
Rachel Zoe
4 Episodes (2009-2014)
Seal
4 Episodes (2003-2016)
Vern Yip
4 Episodes (2003-2010)
Lil' Romeo
4 Episodes (2002-2005)
Kris Allen
4 Episodes (2009-2012)
Andy Cohen
4 Episodes (2011-2016)
Ross Lynch
4 Episodes (2013-2015)
Adam Brody
3 Episodes (2004-2007)
Ali Larter
3 Episodes (2007-2009)
Anna Faris
3 Episodes (2008-2013)
Bernie Mac
3 Episodes (2002-2007)
Bow Wow
3 Episodes (2002-2008)
Bow Wow
3 Episodes (2002-2008)
Cher
3 Episodes (2010-2014)
David Muir
3 Episodes (2014-2016)
Demi Moore
3 Episodes (2008-2010)
Ed O'Neill
3 Episodes (2001-2016)
Elton John
3 Episodes (2001-2014)
Eve
3 Episodes (2002-2004)