Life on NBC

What can you spill about the Grey's Anatomy season finale? Are we definitely saying goodbye to George and T.R. Knight? — Kellie
MATT: Yes, there are rumors swirling that the finale not only paves the way for George's departure ... read more 39 Comments

The senior editors of TVGuide.com hope the following shows will live. We chose them because we consider them the best of the shows that are in the worst danger. Make the jump to review our picks, then follow TV Guide on Twitter for updates on saved shows. read more 232 Comments

I adored the "McFamily" scenes last week on Grey's Anatomy. What's next for Mark, Lexie, Meredith and Derek? — Kelly
MATT: For Mark and Lexie, much cuteness is on the immediate horizon. I mean, as much as Thatcher Grey makes my skin crawl (no offense, Jeff Perry!), the way things play out when he returns is better than I expected. For Mer and Der, there's the none-too-small matter of a stern ultimatum coming from the bride. As that gets sorted out, the would-be marrieds will find cause to fast-track their wedding, so get to updating that website, illing Izzie! 

So I'm guessing that Gaby will be hosting the spoiled teen diva on Desperate Housewives. They should totally get Selena Gomez to play the part! — Darcy
MICKEY: I like where your head's at, Darcy, what with the Disney/ABC corporate synergy and all. It won't be Selena, but the Housewives casting elves ... read more 51 Comments

Wednesday's ratings rundown:

8 pm/ET
Lie to Me topped the hour with an audience of 8.42 million total viewers, down 560K week-to-week. CBS' Old Christine and Gary Unmarried combined for second, both delivering 7.3 mil.

ABC's sitcoms, meanwhile, lagged behind a Law & Order repeat, with Scrubs managing 4.67 mil (down 335K) and Better Off Ted drawing 4.2 mil (down 500 thou). Top Model tallied 3.7 mil, dipping 250K.

9 pm
American Idol ruled with 22.43 million viewers, slipping 5 percent week-to-week. Criminal Minds followed with 13.25 mil, dropping 750 thou. Lost lost 12 percent of its last audience, hitting 8.3 mil.

NBC's Life wrapped up its sophomore run with an audience of 4.5 mil, plunging 19 percent. Will Life go on? Although it might seem unlikely, there is talk of struggling NBC picking up "mini" seasons of a few on-the-bubble series. Stay tuned.

10 pm
CSI: NY was No. 1 with 12.5 mil, followed by the premiere of ABC's The Unusuals, which copped 6.84 million viewers. As a benchmark of sorts, Life on Mars' first après-Lost outing grabbed 300K fewer heads than that.