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His health and private life, marriage and family, the myth of Camelot, and finally, his assassination and legacy.
The events in Southeast Asia that eventually led to America's war in Vietnam.
Civil Rights, from his record as a senator up though the transformation near the end of his life that would help inspire the Civil Rights Act of 1964.
The origins of Soviet-American tensions in the divided city of Berlin from the final days of World War II up through the time of John F. Kennedy's Presidency.