Premise

The classic Gloria Monty soap charting the trials of Port Charles' medical center. Even daytime naysayers tuned in to see the celebrated nuptials of supercouple Luke and Laura, who scored covers of both Time and Newsweek during the same month. Over time, the series flirted with sci-fi, sexy aliens, adventurous location shoots and a late '90s mafia madness. It debuted on April Fools' Day 1963 and spun off the gothic guilty pleasure that was `Port Charles' (which was canceled in 2003).

Cast

Former Cast

Anna Lee
Lila Quartermaine
2596 Episodes (2001-2016)
Anne Jeffreys
Amanda Barrington
2596 Episodes (2001-2016)
Corbin Bernsen
John Durant
2596 Episodes (2001-2016)
Demi Moore
Jackie Templeton
2596 Episodes (2001-2016)
Janine Turner
Laura Templeton
2596 Episodes (2001-2016)
Johnny Jensen
Scotty Baldwin
2596 Episodes (2001-2016)
Katie Stuart
Sage Alcazar
2596 Episodes (2001-2016)
Mark Hamill
Kent Murray
2596 Episodes (2001-2016)
Martin West
Dr. Phil Brewer
2596 Episodes (2001-2016)
Ross Elliott
Lee Baldwin
2596 Episodes (2001-2016)
Susan Seaforth
Dorothy Bradley
2596 Episodes (2001-2016)
Jacob Young
Lucas Lorenzo `Lucky' Spencer Jr.
2596 Episodes (2001-2016)
Alicia Leigh Willis
Courtney Matthews
2596 Episodes (2001-2016)
Jed Allan
Edward Quartermaine
2596 Episodes (2001-2016)
Lesli Kay
Lois Cerullo
2596 Episodes (2001-2016)
Shaun Benson
Steven Lars Webber
2596 Episodes (2001-2016)
Teddy Quinn
Scotty Baldwin
2596 Episodes (2001-2016)
Coltin Scott
Nikolas Cassadine
2596 Episodes (2001-2016)
Don Clarke
Scotty Baldwin
2596 Episodes (2001-2016)
Tony Campo
Scotty Baldwin
2596 Episodes (2001-2016)
Jen Lilley
Maxie Jones
2596 Episodes (2001-2016)
Aaron Revfem
Morgan Corinthos
2596 Episodes (2001-2016)
Emily Wilson
Ellie Trout
2596 Episodes (2001-2016)
Tyler Christopher
Nikolas Cassadine
2421 Episodes (2003-2016)
Jason Thompson
Dr. Patrick Drake
2281 Episodes (2006-2016)
Anthony Geary
Lucas Lorenzo Spencer
2196 Episodes (2001-2015)
Jacklyn Zeman
Bobbie Spencer
1933 Episodes (2006-2016)
Julie Marie Berman
Leslie Lu `Lulu' Spencer
1585 Episodes (2006-2013)
Steve Burton
Jason Morgan
1486 Episodes (2002-2013)
John Ingle
Edward Quartermaine
1415 Episodes (2006-2013)
Brandon Barash
Johnny Zacchara
1374 Episodes (2008-2016)
Rick Hearst
Ric Lansing
1134 Episodes (2002-2016)
Wally Kurth
Ned Ashton
938 Episodes (2006-2015)
Teresa Castillo
Sabrina Santiago
926 Episodes (2013-2016)
Bryan Craig
Morgan Corinthos
881 Episodes (2013-2016)
Megan Ward
Kate Howard
864 Episodes (2008-2011)
Bruce Weitz
Anthony Zacchara
783 Episodes (2007-2012)
Rachel Ames
Audrey March
745 Episodes (2006-2013)
Ignacio Serricchio
Diego Alcazar
745 Episodes (2006-2011)
Kent King
Dr. Lainey Winters
744 Episodes (2006-2011)
Natalia Livingston
Emily Bowen Quartermaine
721 Episodes (2003-2013)
Jason Cook
Matt Hunter
714 Episodes (2010-2012)
Nathan Parsons
Ethan Lovett
714 Episodes (2010-2012)
Scott Reeves
Steven Webber
709 Episodes (2010-2013)
Greg Vaughan
Lucas Lorenzo `Lucky' Spencer Jr.
698 Episodes (2006-2013)
Dylan Cash
Michael Corinthos
656 Episodes (2006-2011)
Brianna Brown
Lisa Niles
655 Episodes (2010-2012)
Dahlia Salem
Claire Walsh
651 Episodes (2010-2012)
Aaron Sanders
Morgan Corinthos
630 Episodes (2010-2012)
Adrianne Leon
Brook Lynn Ashton
619 Episodes (2010-2012)
Kristen Alderson
Starr Manning/Lauren Katherine "Kiki" Jerome
592 Episodes (2012-2015)
Adrienne Barbeau
Suzanne Stanwyck
573 Episodes (2010-2012)
Jeffrey Vincent Parise
José "Joe" Rivera/Carlos Rivera
559 Episodes (2014-2016)
Jonathan Jackson
Lucas Lorenzo `Lucky' Spencer Jr.
542 Episodes (2009-2013)
Kelly Sullivan
Kate Howard/Connie Falconeri
529 Episodes (2011-2013)
Kelly Thiebaud
Britt Westbourne
509 Episodes (2013-2015)
Stuart Damon
Dr. Alan Quartermaine
465 Episodes (2008-2013)
Sean Kanan
A.J. Quartermaine
403 Episodes (2012-2014)
Sarah Brown
Carly Benson/Claudia Zacchara
376 Episodes (2008-2013)
Jimmy Deschler
Rafe Kovich Jr.
375 Episodes (2013-2014)
Ilia Volok
Andre Karpov
365 Episodes (2008-2011)
Richard Burgi
Paul Hornsby
346 Episodes (2015-2016)
Elena Tovar
Rosalie Martinez
316 Episodes (2014-2015)
Ted King
Lorenzo Alcazar
313 Episodes (2006-2010)
Scott Clifton
Dillon Quartermaine
290 Episodes (2006-2013)
Vanessa Marcil Giovinazzo
Brenda Barrett
258 Episodes (2002-2013)
Jesica Ahlberg
Darby Collette
235 Episodes (2015-2016)
Tristan Rogers
Robert Scorpio
216 Episodes (2006-2014)
Pepi Sonuga
Taylor DuBois
190 Episodes (2013-2014)
Thaao Penghlis
Victor Cassadine
173 Episodes (2013-2015)
Grayson McCouch
Kyle Sloane
154 Episodes (2015-2015)
Drew Garrett
Michael Corinthos
150 Episodes (2009-2010)
Bradley Cole
Warren Bauer
147 Episodes (2010-2010)
Lindsey Morgan
Kristina Corinthos Davis
134 Episodes (2012-2013)
Samantha Logan
Taylor DuBois
115 Episodes (2013-2013)
Josh Duhon
Logan Hayes
99 Episodes (2008-2009)
Robin Riker
Naomi Dreyfus
97 Episodes (2016-2016)
Ashley Jones
Parker Forsyth
92 Episodes (2016-2016)
James Franco
Franco
87 Episodes (2009-2011)
Erik Valdez
Trey Mitchell
80 Episodes (2012-2013)
Donna Mills
Madeline Reeves
79 Episodes (2014-2015)
Brad Rowe
Murphy Sinclair
59 Episodes (2010-2010)
Robin Mattson
Heather Grant Webber
17 Episodes (2012-2013)
Antonio Sabato Jr.
Jagger Cates
17 Episodes (2006-2013)
Jack Wagner
Frisco Jones
6 Episodes (2012-2013)
Tamara Braun
Carly Benson
6 Episodes (2002-2013)
Emma Samms
Holly Sutton
5 Episodes (2012-2013)
Brad Maule
Dr. Tony Jones
5 Episodes (2012-2013)
Chris Robinson
Dr. Rick Webber
4 Episodes (2013-2013)
Denise Alexander
Dr. Lesley Williams
3 Episodes (2013-2013)
John Beradino
Dr. Steve Hardy
3 Episodes (2013-2013)
Amber Tamblyn
Emily Bowen Quartermaine
2 Episodes (2011-2013)
Elizabeth Taylor
Helena Cassadine
2 Episodes (2012-2013)
John Stamos
Blackie Parrish
2 Episodes (2013-2013)
Richard Dean Anderson
Dr. Jeff Webber
2 Episodes (2013-2013)
Kristina Malandro
Felicia Cummings
2 Episodes (2013-2013)
Sharon Wyatt
Tiffany Hill
2 Episodes (2013-2013)
Steve Bond
Jimmy Lee Holt
1 Episode (2013)
David Lewis
Edward Quartermaine
1 Episode (2013)
Susan Brown
Dr. Gail Adamson
1 Episode (2013)
Krys Meyer
T.J. Ashford
1 Episode (2012)

Guest Stars

Jane Elliott
Tracy Quartermaine
31 Episodes (2006-2010)
Claire Coffee
Nadine Crowell
18 Episodes (2008-2008)
Stephen Macht
Trevor Lansing
17 Episodes (2008-2008)
Daniel Benzali
The Balkan, Theo
12 Episodes (2010-2011)
Kristina Wagner
Felicia, Felicia Jones
9 Episodes (2012-2013)
Michael Sutton
Stone, Stone Cates
6 Episodes (2010-2013)
Stephen Nichols
Stefan, Stefan Cassadine
5 Episodes (2003-2013)
Christian Alexander
5 Episodes (2010-2010)
Rena Sofer
Lois Ashton, Lois Cerullo
4 Episodes (2010-2013)
Billy Warlock
AJ Quartermaine
3 Episodes (2013-2013)
George Gaynes
Frank Smith
3 Episodes (2013-2013)
Jana Taylor
Angie Costello
2 Episodes (2013-2013)
K.T. Stevens
Peggy Mercer
2 Episodes (2013-2013)
Mary Beth Evans
Katherine Bell
2 Episodes (2013-2013)
Roy Thinnes
Phil Brewer
2 Episodes (2013-2013)
Cari Shayne
Karen Wexler
2 Episodes (2013-2013)
Chad Brannon
Zander, Zander Smith
2 Episodes (2003-2013)
Ricky Martin
Miguel Morez
2 Episodes (2010-2013)
Gail Ramsey
Susan Moore
2 Episodes (2013-2013)
Susan Pratt
Anne Logan
2 Episodes (2013-2013)
Dakin Matthews
Judge Carroll
1 Episode (2010)
Ian Buchanan
Duke Lavery
1 Episode (2013)
John Colicos
Mikkos Cassadine
1 Episode (2013)
Lisa Marie
Jennifer Smith
1 Episode (2013)
Seamus Dever
Dr. Ian Devlin
1 Episode (2008)
Shirley Jones
Mrs. McClain
1 Episode (2014)
Melissa Peterman
Melissa Santoro-Picard
1 Episode (2015)
Lisa Cerasoli
V "Venus" Ardonowski
1 Episode (2013)
Leslie Horan
Miranda Jamison
1 Episode (2010)
Ross Thomas
Brandon
1 Episode (2011)
Derek Theler
Derek
1 Episode (2015)