William pens Jamie a love letter while pondering suicide; Bondurant gets devastating news about his musical aspirations; Jamie sets out to reinvent herself; and Mitzi is rushed to the hospital after collapsing.
Jamie ushers William to a secret party that is being thrown in his honor; Mitzi and Bondurant's Thanksgiving at his father's cabin is interrupted by an unexpected guest; Jamie discovers something shocking about the subject of William's novel.
When a coalition of artists and scientists attempt to blow up the moon, Bondurant steps in to save the source of his musical talent. Later, William and Jamie get into a serious fight, and Mitzi and William bond over their respective relationship issues.
Jamie tries to help the hospitalized Bondurant who has a respiratory problem and an audition in the morning, while William and Mitzi have a high time hanging out, smoking pot and enjoying their new situation.
The nocturnal misadventures of four twentysomething friends begins with Bondurant admitting his love from William's girlfriend and Mitzi confessing to Jamie that she's pregnant. Later, Bondurant and William break into Massey Hall.