In the series finale, Eli and Keith help a woman in need of a heart transplant who clashes with the family of a potential donor because of her religious views. Meanwhile, Eli's visions of a plane crash cause concern for his loved ones, and Taylor and Matt take another step in their future together.
Jordan and Eli take up the cause of a room-service waiter (Kurt Fuller) who was one of hundreds of employees laid off from a failed financial institution that awarded its former CEO a multimillion-dollar golden parachute. Meanwhile, Eli's latest vision involves his father and an airplane.
When Eli represents a newscaster who has lost his job, Eli's relationship with Maggie reaches new levels both inside and outside of court. Meanwhile, Matt faces a difficult decision concerning the fate of his former firm.
Getaway plans for Taylor and Matt morph into a road trip with Eli and Maggie to Sonoma, where a witness in an important case is in jail, but the efforts to get her released are hampered by Matt's history with a local judge. Meanwhile, Eli's dangerous flirtation with a risky acupuncture procedure results in a new health crisis.
Nate's request for Eli to officiate at his wedding coincides with Eli's speculation about the level of his fiancée's commitment, which sends the younger Stone to another acupuncturist for a risky procedure that could provide a glimpse of the future. Meanwhile, a minister needs Keith and Eli's help to fight charges of discrimination, and Taylor and Matt learn unsettling news about her pregnancy.
Eli is ready to tell Ashley (Bridget Moynahan) about his gift of prophecy, but her reaction sends him to a rival of Dr. Chen's to look into the future of his love life. Meanwhile, Eli's latest vision convinces him to take the case of a Nobel Prize winner, and Taylor represents Jordan in his divorce from her stepmother.
Bridget Moynahan guest stars as a love interest for Eli, whose latest vision has an impact on his and Keith's defense of Patti's daughter on drug charges. Meanwhile, Matt acquires tickets to see Taylor's favorite singer, Seal, who appears as himself.
Eli's latest vision puts him in his father's body on Nate's 12th birthday, which gives him insight on a case involving a teen's wish to be emancipated from his formidable father, who is represented in court by Matt and Maggie. Meanwhile, Taylor struggles to tell Matt she's pregnant, and Keith tries to steer clear of Patti's daughter.
In an effort to keep the new firm in the black, Eli faces a moral dilemma during the course of persuading a philanthropist to back a trial to test the effectiveness of medical marijuana. Meanwhile, Keith helps Patti's daughter after she's arrested, and Matt and Maggie try to unmask a spy for the rival Posner/Klein.
Amid the fallout from the seismic split at the firm, the scramble to keep clients and employees from jumping ship to a rival includes Eli's efforts to show Matt the rewards of pro bono work on a case involving Homeland Security. Meanwhile, the truth about Maggie's fiancé is revealed in Eli's latest vision.
A rift develops between Eli and Jordan when the former takes on a paint manufacturer and the latter must defend himself against charges of insanity. Meanwhile, Eli learns an important lesson about his visions from his father's diary.
Eli begins a fling with an attorney (Katie Holmes) he meets at a baseball game---after already having seen her singing to him in one of his visions. Meanwhile, Eli and Maggie help a man that wants to put a stop to a military burial for his son, who died in Iraq.
Sigourney Weaver guest stars in the second-season premiere, which finds Eli vision-free for six months following the surgery to remove his brain aneurysm. However, hallucinations now seem to be happening to his brother, Nate, who believes he knows where Jordan is after a crane accident traps him in a building.