Four murders occur during Fashion Week in New York City when rage overtakes seemingly ordinary individuals with no prior history of violence. Hood investigates to discover what triggered the homicidal outbursts.
Hood investigates when a woman's frozen body is discovered on a hot California beach and shows no signs of thawing. The investigation reveals that the victim had a terminal blood disease, but it had nothing to do with her death. Later, another person with a fatal illness is found frozen in an office building. Hood learns that both victims may be linked to a foundation that promises people immortality.
Hood and Rachel travel to a small Georgia town to investigate the deaths of three seemingly healthy 11-year-old boys who died of heart attacks. Tension rises among the locals as fear overtakes them and another boy collapses.
Top biophysicist Jacob Hood (Rufus Sewell) investigates crimes of a scientific nature for the FBI. In the series opener, evidence is discovered that suggests someone is attempting to clone humans. Nineteen buried fetuses are found near Seattle and the probe reveals they all have the same DNA.