Three gang members burst into the emergency room to kill a wounded rival and then hold several doctors and patients hostage when police arrive before they can escape. DeWayne: David Batiste. Marcus: Aldis Hodge. Isaac: Antwon Tanner. Sammy: Jacob Huang. Ben: Blair Underwood. Stewart: Kyle Secor. Ellis: Gabrielle Union.
A 12-year-old Somalian girl bleeding from a ritual circumcision is brought in by her older sister; a kidney becomes available to transplant but the patient can't be found; a husband isn't sure if he wants his wife to get reconstructive surgery that will make her beautiful; Ben receives two unexpected kisses from two different woman. Ben: Blair Underwood. Stewart: Kyle Secor. Courtney: Gabrielle Union.
Ben is suddenly stricken with a mysterious illness that leaves him unable to speak clearly; Ellis goes against orders to help a dying patient; Stewart hesitates to perform reconstructive surgery on a woman when her husband objects to it; a transsexual stabs herself in the leg to get the doctors to perform surgery on her. McKenna: Saundra Quarterman. LaWanda: Allan Louis. Salmon: Harry Groener. Ben: Blair Underwood. Stewart: Kyle Secor. Ellis: Gabrielle Union.
Ben is asked by a terminally ill teen (Kenny Blank) to not perform a scheduled operation on him, even though his parents want it done; Williams orders a Thanksgiving turkey from a questionable source and is surprised at how fresh it really is; an elderly woman (Starletta DuPois) who claims she can sense when death is approaching a person, causes Stewart and Ellis to rethink a patient's diagnosis. Maxine: Akuyoe Graham. Joe: Basil Wallace. Wendell: Harold Sylvester. Rosa: Christine Avila.
Dr. Chanley is an emotional wreck after she performs a life-altering operation on the wrong patient and then informs Ambrose that she's pregnant with his child, which he doesn't want; Syphax and Jackson are rudely received when they drive the hospital's new mobile diagnostic vehicle into a rough neighborhood. Dr. Chanley: Paula Newsome. Norma: Michelle Bonhill. Vasquez: Jose Yenque. Salimpour: Shishir Kurup. Syphax: Tamara Taylor. Ambrose: Gregalan Williams. Bennett: Corey Mendell Parker.
After Ambrose botches an operation, Ben and Stewart go behind his back and perform the correct surgery, which leads Ambrose to discipline them both. Also, a patient keeps eating people's possessions; Ellis's misdiagnosis nearly costs a boy his life; Chanley receives some disturbing news. Ambrose: Gregalan Williams. Stewart: Kyle Secor. Ellis: Garbrielle Union.
Nurses threaten to walk off the job unless a rapist is caught; Ben suggests Ambrose step aside during a complicated surgery; Gwen is confronted by the brother who once raped her; Damon is furious after being demoted by Ben for trying to cover up a near-fatal mistake. Damon: Bokeem Woodbine. Ambrose: Gregalan Williams. Helen: Paula Newsome. Curtis: Hawthorne James. Terry: Roger Guenveur Smith. Gwen: Sandi Schultz. Ben: Blair Underwood.
Ben's mentor, Dr. Langston Ellis (Clifton Davis), visits the hospital and quickly causes problems with his condescending attitude; the rapist terrorizing the hospital strikes again; a gunshot groom refuses surgery until he is married to his bride, who is about to give birth to their baby. Mary: Cynthia Martells. Helen: Carol Woodbury. Uri: George Tasudis. Svetla: Olga Vilner. Courtney: Gabrielle Union. Ben: Blair Underwood.
Ellis works overtime to prepare for her father's impending visit, causing her to grow cranky to the point of mistreating an obese patient (Joe Costanzo); a circus clown attempts suicide; Peeler unwittingly gives damaging testimony against Ben; Grace breaks up with Weiss. Happy: Raymond O'Connor. O'Malley: Robert Morse. Elliot: Mark Kiely. Mason: Bruce French. Gwen: Sandi Shultz. Captain: Joseph Griffo. Damon: Bokeem Woodbine. Gill: Gregg Daniel. Harris: Michael Warren. Ben: Blair Underwood.
A rapist terrorizes the hospital and causes the nurses to refuse to work night shifts. Also, Ben clashes with the medical director (Gregalan Williams), and welcomes a new plastic surgeon (Kyle Secor) and a new psychiatrist (Sandi Schultz). Damon: Bokeem Woodbine. Marcus: Aldis Hodge. Donato: Java Benson. Carter: Ron Canada. Ellis: Gabrielle Union. Ben: Blair Underwood.