The actor talks about his new sitcom with the comedian. Plus, hear how he and his wife juggle taking care of six children!
Would you have the wherewithal to punch a shark in the face if it was trying to eat you? Watch the panelists joke about Syfy's latest movie.
Chelsea and the panel chide the runner-up for calling out Andi Dorfman for making love before dumping him. Seriously, bro?
The "Chelsea Lately" panel sounds off on the "Kardashians" star's "Many Moods of Me" photo. Find out why it's leaving everyone speechless!
The "Leftovers" actor reveals to Chelsea why he always gives eggs as gifts. Plus, hear why he likes to bartend at parties and who is Chelsea Hander?
Hear Uzo Aduba and Natasha Lyonne describe the abandoned children's ward where "Orange Is the New Black" films. That sounds really weird!
Carly and Danielle from the daily online newsletter bring Chelsea and Chuy up to speed on world news in this funny segment. Check it out!
The actress admits to her obsession with sex! Plus, find out why Jenny is in a fashion war with Dolce & Gabbana.
The "Resident Evil" actress calls out Chelsea's stalking behavior. Plus, Milla reveals her hot and heavy relationship with Robert De Niro!
The country crooner brings congratulatory gifts for Chelsea on her 600th show celebration. Plus, listen in on their vodka bonding!
The "Purge: Anarchy" star tells the story of a pub crawl gone horribly wrong. Stick around for the priceless punchline in this clip from "Chelsea Lately."
Chelsea and the panel discuss the big reveal by Marvel that came out of Comic-Con. See them riff on the event's fans on "Chelsea Lately."
The Starz stunner says working for the rapper has been awesome! Plus, get her take on acting in the drug drama's sex scenes.
What do Chelsea and the panel think of the former "View" host's attempt to back out of a surrogate pregnancy? Hear their harsh criticism!
The "Breaking Bad" actor spills what he'll be up to in Rome! Hear about his role as the famous inventor--and what stunt body part he'll be wearing!
Download the TV Guide app for iPhone, iPad and Android!