Catherine experiences hallucinations but refuses to be admitted to the hospital. Meanwhile, Bickman is hesitant to operate again after a botched surgery; and the team questions a woman's motives after she confronts a man with a knife.
A doorman collapses, so Dr. Bickman rushes him to the Cube and performs an alternative procedure. Meanwhile, Catherine gets depressed after making a tough diagnosis; Joshua fears he's enabling his sister; and Catherine breaks up with Will.
A patient who thinks he's dead is admitted by Dr. Morely. Meanwhile, a mom fears her daughter has meningitis; Esme begins working at Will's restaurant; and Catherine reveals a secret to Will, but it's not what he was expecting to hear.
Catherine conducts a study on music, which includes a patient who's developed a pitch problem and a man who's acquired savant syndrome. Meanwhile, someone unexpected is sought to help a musician with tremors; and Dr. Bickman makes a surprising proposal.
Dr. Bickman and Dr. Black work to remove a bullet from a Pulitzer Prize-winning journalist without help from modern technology. Meanwhile, a high-profile makeup artist suffers a minor stroke leaving him color blind; and Catherine meets Will's parents.
Catherine and Joshua reflect on their past when their father returns. Meanwhile, a decorated soldier struggles with a war wound; a new patient is admitted to the Cube after falling off a mountain; and Will tries to get rid of Delilah.
World-famous neuroscientist Catherine Black has a special touch with her patients but struggles with her own mental illness in this drama series. In the opener, Catherine meets a new colleague and deals with pressure from her boyfriend, who wants to make their relationship more serious.