Premise

Two nerdy physicists share an apartment and an unlikely friendship with their beautiful neighbor with whom one of them is infatuated. Like the universe after the big bang, the show's popularity expanded, thanks to breakout star Jim Parsons, along with the chemistry among the friends and the developing romance between Leonard and Penny. The addition of Melissa Rauch and Mayim Bialik in later seasons also enhanced the stories and relationships of the leads.

Cast

Guest Stars

Kevin Sussman
Stuart
40 Episodes (2009-2016)
Carol Ann Susi
Mrs. Wolowitz
21 Episodes (2008-2014)
Sara Gilbert
Instructor, Leslie Winkle
20 Episodes (2007-2016)
John Ross Bowie
Barry Kripke, Kripke
18 Episodes (2009-2016)
Laura Spencer
Ellen, Emily
14 Episodes (2014-2016)
Wil Wheaton
Himself
13 Episodes (2009-2016)
Christine Baranski
Beverly, Beverly Hofstadter, Dr. Beverly Hofstadter
8 Episodes (2009-2016)
Laurie Metcalf
Mary, Mary Cooper
8 Episodes (2007-2016)
Alice Amter
Mrs. Koothrappali
8 Episodes (2007-2012)
Brian George
Dr. Koothrappali, Dr. V.M. Koothrappali
7 Episodes (2007-2014)
Carol Ann Susi
Mrs. Wolowitz, Mrs.Wolowitz
7 Episodes (2008-2014)
Casey Sander
Mr. Rostenkowski
6 Episodes (2012-2015)
Mark Harelik
Dr. Eric Gablehauser, Gablehauser
5 Episodes (2007-2008)
Bob Newhart
Prof. Proton, Prof. Proton/Arthur, Professor Proton
4 Episodes (2013-2015)
Regina King
Mrs. Davis
4 Episodes (2013-2014)
Alessandra Torresani
4 Episodes (2016-2016)
Sara Rue
Stephanie
3 Episodes (2008-2008)
Joshua Malina
Pres. Seibert, Presdient Siebert
3 Episodes (2011-2012)
Stephen Merchant
Dave, Ethan
3 Episodes (2015-2015)
Marcus Folmar
Guard, Police Officer, Security Guard
3 Episodes (2010-2016)
Dakin Matthews
2 Episodes (2012-2014)
Keith Carradine
2 Episodes (2010-2015)
LeVar Burton
Himself
2 Episodes (2012-2014)
Stephen Root
2 Episodes (2014-2014)
Brian Posehn
2 Episodes (2013-2014)
Katee Sackhoff
Herself
2 Episodes (2009-2010)
Ira Flatow
Himself
2 Episodes (2009-2013)
Alex Ball
Waiter
2 Episodes (2013-2014)
Molly Morgan
Bethany, Hostess
2 Episodes (2009-2015)
Analeigh Tipton
Analeigh, Vanessa
2 Episodes (2008-2015)
Josh Brener
2 Episodes (2011-2013)
Adam West
Himself
1 Episode (2016)
Billy Bob Thornton
Dr. Oliver Lorvis
1 Episode (2014)
Brent Spiner
Himself
1 Episode (2011)
Carrie Fisher
Herself
1 Episode (2014)
D.J. Qualls
1 Episode (2008)
Eliza Dushku
FBI Agent
1 Episode (2010)
Jane Kaczmarek
Dr. Gallo
1 Episode (2016)
Jessica Walter
Mrs. Latham
1 Episode (2011)
Joel Brooks
Professor Goldfarb
1 Episode (2008)
Judd Hirsch
Alfred
1 Episode (2016)
Judy Greer
Dr. Elizabeth Plimpton
1 Episode (2010)
Kevin Smith
Himself
1 Episode (2015)
Steve Valentine
Kenneth
1 Episode (2014)
Troy Winbush
Paramedic No. 2
1 Episode (2013)
Elizabeth Bogush
Dr. Catherine Millstone
1 Episode (2009)
Nathan Fillion
Customer
1 Episode (2015)
Rick Fox
Glenn
1 Episode (2011)
Summer Glau
Herself
1 Episode (2009)
Bill Nye
Himself
1 Episode (2013)
Tania Raymonde
1 Episode (2014)
Oliver Muirhead
Professor Laughlin
1 Episode (2009)
Paul Wilson
Prof. Thorne
1 Episode (2014)
Meagan Fay
Mrs. Rostenkowski
1 Episode (2012)
Josh Peck
Jesse
1 Episode (2014)
Lewis Black
Professor Crawley
1 Episode (2009)
Stan Lee
Himself
1 Episode (2010)
Buzz Aldrin
Himself
1 Episode (2012)
June Squibb
Meemaw
1 Episode (2016)
Mark Barrett
Security Guard No. 2
1 Episode (2015)
Octavia Spencer
Octavia
1 Episode (2008)
Steve Wozniak
Himself
1 Episode (2010)
Tiffany Dupont
1 Episode (2011)
Valerie Azlynn
1 Episode (2009)
Tate Ellington
Mitchell
1 Episode (2015)
Max Adler
Zombie
1 Episode (2015)
Lanny Joon
Officer Shin
1 Episode (2011)
Steven Yeun
Sebastian
1 Episode (2010)
Barak Hardley
Pizza Delivery Guy
1 Episode (2013)