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After Astro regains his memory and returns home to Dr. O'Shay, Dr. Tenma vows revenge and stages a high-tech attack on the Ministry of Science. Can Astro reason with him in time to save the Ministry?
When Astro is damaged during Drake's missile attack, Dr. Tenma must repair him. But Tenma intentionally wipes out all of his memory, and it's up to Zoran to reunite Astro with his family.
General Red and the human military are preparing to fire the Pulsar Laser Cannon to destroy Robotonia and all of its robots. Astro and The Blue Knight must join forces to foil the attack.
The battle between robots and humans continues as Astro finds himself caught in the fight between The Blue Knight's rebel robot-force and Drake's anti-robot group.