In the first-season finale, Michael discovers a patient at the clinic has a special link to Anna. Meanwhile, Michael gets reacquainted with an old friend who's been diagnosed with an uncommon illness.
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Michael's high-school girlfriend arrives at Holy Neuro with a grave condition, and he has trouble accepting the limits of what he can do to help her. Meanwhile, Zeke learns that his best friend is battling a cancer relapse.
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A pampered pop star arrives at Holt Neuro with atypical symptoms similar to those experienced by a young girl at the clinic. The doctors at both medical facilities then work together to try and find an underlying connection.
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The clinic staff are held hostage by a woman who becomes unhinged following Michael's testimony in a case involving a former patient.
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Michael rescues a man from drowning, but the man's identity is unknown. Elsewhere, Kate realizes that she's been oblivious to the problems facing a girl she's mentoring.
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Michael and E-Mo butt heads over treating a patient who has a brain tumor. Meanwhile, a teenage girl abandons her newborn soon after giving birth at the clinic.
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Michael's clinic colleagues rush to operate on him after he exhibits signs of a dire condition requiring immediate medical attention.
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Kate and Michael team up to help a clinic patient who contracted a deadly virus. Meanwhile, Michael treats an anxious bride with headaches and observes that her mother (Faith Prince) is showing signs of a grave illness.
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Rita and her husband (Tom Wopat) want Michael to operate on their son after he gets injured in a motorcycle accident on Thanksgiving. Elsewhere, Kate and Zeke revive a patient who has a DNR order.
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The heinous criminal actions of a brain-tumor patient (John Benjamin Hickey) weigh on Michael as he makes a choice about saving the man's life. Meanwhile, a seemingly disoriented female firefighter (Mamie Gummer) is examined at Holt Neuro.
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Michael is surprised to see an ex-football star whom he once treated now getting help at the clinic because he's homeless. Meanwhile, Michael deals with a case of post-traumatic stress disorder at his practice.
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A neuropsychiatrist (Eriq La Salle) impresses Michael by diagnosing a patient based on her body language, so Michael invites him to join his practice. Meanwhile, Michael faces a situation with a patient that could jeopardize his practice.
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Michael seeks Anton's assistance with a patient who's hearing voices. Elsewhere, Kate has a rough first day at the clinic.
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Michael operates on a woman with brain lesions even though he doesn't know the root of the problem. Meanwhile, a new doctor must be found to run Anna's clinic.
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Michael tries to help his pregnant friend who has a brain tumor, while also treating a young boy with sickle-cell anemia at Anna's old clinic.
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Pilot
Season 1, Episode 1
In the series premiere of this drama, a top-notch neurosurgeon (Patrick Wilson) begins receiving visits from the ghost of his ex-wife (Jennifer Ehle), who teaches him what's important in life. Shortly after her first visit, she asks him to help out at a low-income clinic where she worked.
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