Universal/Everett Collection; Colleen Hayes/NBC
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NBC originally tried to turn the hit 1989 Steve Martin film into a TV show back in 1990. Despite a cast of such future stars as Leonardo DiCaprio, Thora Birch and David Arquette (not to mention writer Joss Whedon), the dramedy only lasted one season. NBC was much more successful in 2010 when a post-FNL Jason Katims loosely adapted the series. The family drama starring Peter Krause, Lauren Graham, Erika Christensen and Dax Shepard, has become fan favorite thanks its relatable (and often heart-wrenching) storylines.