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Lexie Grey, Grey's Anatomy
Little Grey's death was by far the most shocking and emotional of the season — especially since the ABC medical drama killed her off only 20 minutes into the finale. We were a blubbering mess when Mark held Lexie's hand and told her how they would someday be married with kids. But we really lost it when Meredith realized she'd never get to say goodbye to the sister she almost never knew. Even though Lexie's time was brief, we're glad we got to know her.