2 of 16
Ellen Pompeo — Meredith Grey
"I was offered the role of Meredith. I had done a movie for the studio called Moonlight Mile, so the studio was aware of me. Then... I met Bob Orci and Alex Kurtzman. ... We sat down and talked about me possibly doing an arc on Alias. That didn't happen. Bob and Alex wrote a show called Secret Service. I really wanted to do that and the studio really wanted me to do Grey's instead. I wanted to do the Secret Service pilot that didn't go, of course; me and my brilliant choices. I read Grey's and I went and met Shonda and I decided to come on and do this. It was just an invitation and I happily accepted."