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Sara Ramirez — Callie Torres
"I was performing as the Lady of the Lake in Spamalot. I got a call that several networks had come out to see the show and ABC was one of them and they had expressed interest in working with me on a seven- episode arc for one of their shows. They didn't know which one, so they wanted me to pick. I had done a pilot for ABC before, so we had a relationship already and I was thrilled. They sent me a stack of all the shows currently on the air as well as all their new pilots that had gotten picked up. I watched them all, knowing very well Grey's Anatomy was my favorite show, and that was in the pile. I decided Grey's was the one I wanted to try for... and they said, 'Great! We're going to fly Shonda Rhimes out to see you in Spamalot.' The next morning, we had brunch together, and I suppose that would have been the callback. She could have canceled that appointment if it didn't go well the night before. But she didn't, thank God. She revealed to me that she was going to be writing a character for me opposite George, and I was thrilled because I was in love with the character George O'Malley. Next thing I knew, I was starting to shoot in February of 2006. I felt so lucky."