Question: What was the strange and funky show on HBO that was a sort of risqué sci-fi anthology à la The Outer Limits and Twilight Zone? It had a CGI female robot host. The name of it is totally escaping me and all my friends.
Answer: Sounds like you're thinking of Perversions of Science, a sci-fi-oriented offering from the people who brought you HBO's Tales from the Crypt. As you say, the hostess was a buxom animated android. The lady's name was Chrome and she was voiced by actress Maureen Teefy.
Based on EC Comics' Weird Science, the show featured a pilot episode with a notably apt title, "Dream of Doom." Perversions of Science debuted in 1997 and was gone after just one season.