The hour kicked off with Arsenio Hall joining the ladies' table and the audience chanting "Sher-ri." She then tearfully talked about being "profoundly grateful" for the opportunity.
"This has been one of the best seven years of my life. I tell people, step out of the fear, because I didn't want to take this job, because I'm not a prosecutor, I don't know anything," she said. "I have to say my boss, Barbara Walters, pushed me. I cried in my dressing room for three years saying, 'What am I doing on this table?'"
The pre-taped episode also featured gospel singers Yolanda Adams, Kirk Franklin and Donnie McClurkin and Bell Biv Devoe serenading their friend as well as a video package highlighting some of her best moments and favorite interviews. While the hour was mostly dedicated to Shepherd, it was also Jenny McCarthy's last day. "I only took a little time but I definitely enjoyed every second of The View," she said.
At the end, a tearful Shepherd — whose son sat beside her — said, "When I joined The View seven years ago, [my son] Jeffrey was 2-years-old and I was going through a very public divorce. Now my son is 9-years-old and I'm going through another very public divorce. Let's just say I'm happy that Barbara Walters and Bill Geddie were better at picking co-hosts for this show than I was at choosing my husband. Seriously, I cannot emphasize enough how working on this show has been a dream come true for me. I got to sit across from one of my idols Whoopi Goldberg and I lived out my very own Sister Act working with some of the best women in this business... I talked pop culture and politics. I laughed, I moaned, I cried, but I worked for seven long years to prove I am not Star Jones! I love you all, but it is now time for my new view and I thank you so much for allowing me in your homes for the last seven years and I will see you again real soon."
In June, Shepherd announced she was leaving the show amid rumors she was fired. The following month McCarthy also confirmed her exit and revealed she's going to host her own weekly, hour-long SiriusXM radio show. Former co-host Rosie O'Donnell is returning alongside Whoopi Goldberg for Season 18.
Watch the opening of Monday's show: