When speaking with television critics about her new show in August, O'Donnell listed the comedian, actor, author and musician among possible guests and emphasized her desire to speak with stars who she thinks have something to say. O'Donnell also said she would like to have singer Adele on her show.
Brand, 36, will next be seen in the film adaptation of Broadway's Rock of Ages.
The Rosie Show premieres on Monday, Oct. 10 at 7/6c on OWN.
Are you excited to see Brand sit down with O'Donnell? Who else do you want to see appear on her show?