Rosie O'Donnell and Dylan Walsh in Nip/Tuck by Prashant Gupta/FX Rosie O'Donnell and Dylan Walsh in Nip/Tuck by Prashant Gupta/FX

At FX's TCA press tour session, the veil was lifted on Bradley Cooper's oft-teased-by-Ausiello "mystery role" on Nip/Tuck: The Alias alum will be playing a self-obsessed ladies'-man plastic surgeon (gee, sound familiar?) on the TV show-within-a-show that factors into the new season. (Christian and Sean, now transplanted to L.A., consult on the fictional Nip/Tuck-esque series. As previously reported, Oliver Platt has an arc as an executive producer.)

As for "instantly popular" 2006 guest star Rosie O'Donnell, not only will she reprise her role as Dawn Budge for "several" episodes, but the prospect of a Nip/Tuck spin-off still looms. "We've spoken about it," says series creator Ryan Murphy. "It's an ongoing discussion."