Neil Patrick Harris by Jean-Paul Aussenard/ WireImage.com; Sarah Chalke by Jeffrey Mayer/ WireImage.com Neil Patrick Harris by Jean-Paul Aussenard/ WireImage.com; Sarah Chalke by Jeffrey Mayer/ WireImage.com

The Creative Arts Emmy Awards are going for laughs this year.

Neil Patrick Harris and Scrubs star Sarah Chalke have been enlisted to host the award show, which honors technical and behind-the-scenes achievements.

Trophies will be handed out Sept. 13, and the ceremony will air on E! as a two-hour special on Sept. 20, a day before the Emmy Awards, where you'll be able to catch Harris again.

The 35-year-old snagged his second straight Emmy nomination for supporting actor in a comedy series for How I Met Your Mother, on which Chalke, 31, guest-starred last season as the potential "mother." - Joyce Eng