Amazingly, 80 million American adults had never experienced the joy of Weeds until now. TV Guide Network continues its campaign to build Weeds Awareness and provide hope nationally by airing the award-winning comedy Sunday nights at 9/8c. But with awareness comes responsibility, so TV Guide Network urges viewers to watch Weeds while considering the impact of marijuana.  Here are some of the most memorable anti-drug PSAs of all time:

1. YOUR BRAIN ON DRUGS

TV Guide named this as one of the top 100 television advertisements, and egg sales went through the roof.



2. WEEDS AWARENESS

National Weeds Awareness Week has its own PSA, which strives to become a future classic.

Nobody sports an oversized blazer on the beach as well as Belinda Carlisle.





19.  SNAKE-MAN DRUG DEALER

This creepy spot was applauded by humans but hissed by snakes. 



20.  MCGRUFF AND REGINA DUET

McGruff is back with another anti-drug chart topper. Why wasn't he part of "We Are the World"?



21. GIRL ON TRACKS/DO SOMETHING

Can you say metaphor for "train wreck"?



22. FATHER/SON DRUG TALK

A powerful PSA with a serious twist. 



23.  SURFING MONKEY BANKS

Marijuana IS an expensive habit. Think of all the Snuggies that were sold to stoners.



24.  MONSTER KID

The X-Files approach to anti-drug advertising.

25.  COMEDIENNE

This standup routine about basketball player Len Bias is not funny, and that's the point.