George will play Mattie, the mother of a young child embroiled in a custody battle. Brosnan's widowed character, a novelist, winds up helping Mattie as she fights her father-in-law to keep her child. Anabeth Gish also stars in the miniseries, which is set to shoot in Nova Scotia, Canada.
Bag of Bones is based on a 1998 King novel, which has been adapted by Matt Venne for the mini-series. Mick Garris is directing.
George's other credits include In Treatment, Alias, Thieves and Roar. Bag of Bones will premiere on A&E in late 2011.