Question: I loved the Desmond episode of Lost. Was this the "game changer" that Damon Lindelof referred to in your interview?

Answer: Yes and no. I'll let Damon explain: "This is the first step in setting up the game changer, but the real bomb is still coming," he explained via e-mail. "And when it hits, there will be no doubt as to the fact that it has. I suspect very few people will be asking, 'Was that it?' BTW, you were pretty awesome in Scrubs. I was impressed." (I swear on a stack of Bibles that I didn't make up that last part. Ask Damon yourself next time you see him!)