Ginnifer Goodwin, Rob Lowe

National Geographic has released first look photos of Rob Lowe as President John F. Kennedy and Ginnifer Goodwin as First Lady Jacqueline Kennedy on the set of the upcoming TV movie Killing Kennedy.

Production on the telepic started this week in Richmond, Va., and already has deeply touched Lowe. "Just saw @ginnygoodwin as Jackie Kennedy in the sad and awful blood-stained dress. Extremely emotional," he tweeted on Tuesday.

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The two-hour movie, based on the book by Bill O'Reilly and Martin Dugard, will focus on Kennedy and his assassin Lee Harvey Oswald in the final years leading up to the president's death.

Nat Geo will premiere Killing Kennedy in November, timed to the 50th anniversary of Kennedy's death.