Discussions between Kardashian and the network, which also airs Keeping Up with the Kardashians, are underway, and co-host Giuliana Rancic has voiced her support for Kardashian to join the show, People reports.
Kardashian has often acted as a correspondent for E!'s red carpet coverage of award shows, including the Oscars last month.
Fashion Police is set to return on Monday, March 30 at 9/8c on E!
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