The quartet joins Ellen Pompeo and Patrick Dempsey, who also extended their contracts through Season 12 back in January. ABC has yet to officially pick up Grey's for Season 11, but the announcement is expected soon.
The news comes on the heels of Sandra Oh's upcoming departure from the series after 10 seasons. Current series regulars Tessa Ferrer and Gaius Charles will also exit at the end of the season. As for those sticking around, it's unclear whether Caterina Scorsone, who's currently reprising her Private Practice role as Dr. Amelia Shepherd, will be promoted to series regular in Season 11, though Thursday's episode opened the door to that possibility.
Aside from Pompeo and Dempsey, Chambers (Dr. Alex Karev), Wilson (Dr. Miranda Bailey) and Pickens (Dr. Richard Webber) are the only remaining original actors who are still with the show. Ramirez (Dr. Callie Torres) joined the show in Season 2 before becoming a series regular the following season.
Are you happy that Chambers, Wilson, Pickens and Ramirez are sticking around?
Grey's Anatomy airs Thursdays at 9/8c on ABC. Watch the latest episode here.