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Grey's Exclusive: Mitch Pileggi Returns for Season Premiere

Mitch Pileggi

Grey's Anatomy has prescribed an encore for X-Files alum Mitch Pileggi.

Pileggi, who first guest-starred on the ABC drama toward the end of Season 3, will return for the two-hour Season 6 premiere, again playing hospital board chairman Larry Jennings, TVGuide.com has learned exclusively.

Check out photos from Grey's Anatomy

When Pileggi first appeared as Jennings, the Seattle Grace bigwig required medical attention after a trip to the Amazon left him with a carnivorous fish lodged in an unfortunate part of the anatomy.

For his encore, Pileggi's hospital mucky-muck will have official business to tend to. It perhaps relates to not one but two staff doctors, Izzie Stevens and George O'Malley, looking the Grim Reaper in the eye.

Check out more of last season's cliff-hangers

Grey's Anatomy's season premiere airs Thursday, Sept. 24, at 9 pm/ET.

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