Jon Hamm Jon Hamm

With three-time defending champ Bryan Cranston (Breaking Bad) out of the picture, will Jon Hamm finally win the Best Actor in a Drama Emmy that's eluded him?

Emmys poll: Who's your pick to win lead drama actress?

The Mad Men star, who earned his fourth nomination, has his best chance yet to win his first statuette thanks to Cranston's absence and a killer tape in "The Suitcase," but he's not the only nominee who could be considered overdue. Michael C. Hall (Dexter) is bidding for the fourth time as well, while Hugh Laurie (House) is on his sixth nod.Then there's first-time nominee Timothy Olyphant (Justified), returning nominee Kyle Chandler (Friday Night Lights) and Boardwalk Empire's Steve Buscemi, who already won the Golden Globe and SAG.Who's your pick to win? Vote below.The 63rd Annual Primetime Emmy Awards airs Sunday, Sept. 18 at 8/7c on Fox.