Barrymore walked down the aisle in a Chanel gown — a fitting choice since her husband's father was a former CEO at the clothing company.
This is the third marriage for Barrymore, who was previously married to bar owner Jeremy Thomas for two months in 1994 and comedian Tom Green from 2001 to 2002.
She and Kopelman began dating early last year and they got engaged five months ago. Soon after, it was revealed that Barrymore was expecting her first child.
Barrymore most recently appeared in Big Miracle.