With her nasty role as Reese Witherspoon's Harvard Law rival in Legally Blonde, Selma Blair fears she's "lost any chance of ever being America's sweetheart." Recalls the actress: "I was in a test screening and people were booing at me like I was a killer in a horror movie — I was just cowering in my seat. So I've decided I don't want to play the devil to Reese's angel anymore!"

Though they're nemeses in reel life, the two actresses have been real-life pals since co-starring in 1999's campy Dangerous Liaisons remake, Cruel Intentions. "Reese has been the most caring friend to me," Blair says. "She's really taken me under her wing, always making sure I have somewhere to go for Christmas and Thanksgiving."

She's especially wowed by her pal's ability to juggle an acting career with a husband (their Cruel co-star Ryan Phillippe) and a two-year-old. "I'm in awe of her every day," Blair chuckles. "My cat has fleas right now and I'm ruined — I don't know how I'm going to make it through the week! But she can balance it all. I don't know how she does it."