"Today I interviewed a squirrel in my backyard and then threw to commercial. Somebody help me," he tweeted on what his rep has confirmed to be his real account.
On the page, his location is listed as Los Angeles, and his bio says: "I had a show. Then I had a different show. Now I have a Twitter account."
Only five hours after joining the popular social media site, O'Brien had amassed 165,202 followers. However, only time — and tweets — will tell when or if O'Brien will discuss what's next. Last week, The Wrap reported O'Brien is planning to tour the country with a new live show.
Are you excited to see O'Brien on Twitter?