Busy Philipps by Eric Charbonneau/WireImage.com Busy Philipps by Eric Charbonneau/WireImage.com

Sure, you can catch her soon on How I Met Your Mother ( as Ausiello reported), but sorry, fans of Busy Philipps on ER, this season's second episode could very well be her last. That's when her do-good-doc character Hope leaves for South America to fulfill her Christian mission - you know, as in faith, Hope and charity. "But the door is not closed for a return," NBC sources tell TV Guide.com. "She greatly enjoyed her character and we enjoyed her. She's a lot of fun."

Unfortunately, viewers can probably expect her sex slave, Dr. Morris (Scott Grimes), to be even more annoying than usual when she dumps him for, you know... God. - Reporting by Ileane Rudolph