Jim Parsons, Kaley Cuoco and Simon Helberg Jim Parsons, Kaley Cuoco and Simon Helberg

In its three years on the air, The Big Bang Theory has already survived the writers' strike and three timeslot changes. So how do the show's producers feel about leading off a new Thursday night comedy block this fall?

"It's almost like we're re-launching the show," co-creator and executive producer Chuck Lorre said at the Television Critics Association fall TV previews. "It feels like a do-over in a way."

CBS added just five new prime-time series to its fall lineup, but Big Bang's move after three seasons on Monday has been one of the most talked-about changes to the network's schedule. CBS made the decision to provide a solid lead-in to new fall comedy S#*! My Dad Says.

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"It's an amazing opportunity... I think it's a smart and exciting move CBS is making," co-creator and executive producer Bill Prady said. "We're delighted that they found the confidence in the show to think they could do that."

Despite vote of confidence from CBS, Emmy voters failed to recognize the series with a best comedy series nomination. (Jim Parsons did, however, grab a nod for best actor in a comedy.)

"I find that the way shows get grouped in the Emmys is odd because we all don't do the same thing. I am a huge, huge fan of Glee ... [but] I don't think they do the same thing we do so I'm a little confused by that," Prady said. "I don't necessarily know if we should be competing against them."

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Season 4 also marks a big change for Sheldon, as he embarks on his first romantic relationship with Amy Farrah Fowler (Mayim Bialik

), who was introduced he end of Season 3. "I never thought I'd stumble onto a character he could communicate with," Parsons said. Lorre said it would be a "very specific... unique relationship."Although a possible reconciliation for Penny and Leonard is still very unclear, things may be looking up for Wolowitz (Simon Helberg), thanks to the return of Melissa Rauch as Bernadette. "When she comes back, we're going to have the ability to talk about what happened," Prady said.And as for what happens when it comes time for those pesky contract negotiations? "I'm doing next season for free, I don't know about you guys," Kaley Cuoco joked. "I think it will all be fine in the end."