Dr. Dre, Eminem, Destiny's Child and Madonna were the big winners when nominations for the 43rd annual Grammy Awards were announced this morning in Los Angeles. With five nods, pioneering rapper Dr. Dre tied Beyonce Knowles of Destiny's Child as the most nominated artist. Destiny's Child members LeToya Luckett and LaTavia Roberson and current member Kelly Rowland won four nominations, as did Eminem, whose controversial Marshall Mathers LP is up for Album of the Year. Newlywed Madonna picked up three nominations for her hit single "Music." Also receiving three nods: 'N Sync, U2, Macy Gray and Steely Dan. Rival pop divas Christina Aguilera and Britney Spears will face off in the Best Female Pop Vocal Performance category for "What a Girl Wants" and "Oops!... I Did It Again," respectively. Vying for Record of the Year are Destiny's Child ("Say My Name"), 'N Sync ("Bye Bye Bye"), Madonna ("Music"), U2 ("Beautiful Day") and Macy Gray ("I Try"). The nominees for Album of the Year were the aforementioned Eminem, Beck (Midnite Vultures), Radiohead (Kid A), Paul Simon (You're the One) and Steely Dan (Two Against Nature). The Grammy Awards will be held on Feb. 21. For reaction and analysis, check out Insider.