Cast

Bill Murray Frank Detorri
Chris Rock Voice of Osmosis Jones 'Ozzy'
Laurence Fishburne Voice of Thrax
David Hyde Pierce Voice of Drix
Brandy Voice of Leah
William Shatner Voice of Mayor Phlegmming
Molly Shannon Mrs. Boyd
Joel Silver Voice of Police Chief
Danny Murphy Zookeeper Superintendant
Kid Rock 'Kidney' Rock
Ron Howard Voice of Tom Colonic
Lois Freeman-Fox Editor
Sam Seig Editor
Stephen R. Schaffer Editor
Randy Edelman Musical Composer
Steve Pilcher Production Designer
Sydney J. Bartholomew Production Designer
Arlan Jay Vetter Art Director
Scott Jacobson Set Decorator
Pamela Ball Withers Costumes
Rick Montgomery Casting
William 'Billy Jack' Jakielaszek Special Effects
Jonathan Earl Stein Sound
Randy Thom Sound
Marleen Atler Make Up
Andy King Technical Advisor