1 of 11Katherine Heigl, The Ugly Truth
Izzie Stevens' life may hang in the balance on Grey's Anatomy, but Heigl is alive and kicking in this romantic comedy. She plays a morning show producer who agrees to let a chauvinistic correspondent (Gerard Butler) test his theories on finding love. You already know how this ends up, but hey look, it's the sexy guy from 300!
Photo By: Columbia Pictures